4V8N

The crystal structure of agmatidine tRNA-Ile2 bound to the 70S ribosome in the A and P site.

これはPDB形式変換不可エントリーです。

4V8N の概要

• エントリーDOI: 10.2210/pdb4v8n/pdb
• 分子名称: 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... (58 entities in total)
• 機能のキーワード: ribosome, agmatidine, trna, trnaile2
• 由来する生物種: THERMUS THERMOPHILUS; 詳細
• タンパク質・核酸の鎖数: 116
• 化学式量合計: 4584464.10

構造登録者

Voorhees, R.M.,Mandal, D.,Neubauer, C.,Koehrer, C.,RajBhandary, U.L.,Ramakrishnan, V. (登録日: 2013-02-13, 公開日: 2014-07-09, 最終更新日: 2024-11-13)

主引用文献

Voorhees, R.M.,Mandal, D.,Neubauer, C.,Koehrer, C.,Rajbhandary, U.L.,Ramakrishnan, V.
The Structural Basis for Specific Decoding of Aua by Isoleucine tRNA on the Ribosome
Nat.Struct.Mol.Biol., 20:641-, 2013

PubMed Abstract: Decoding of the AUA isoleucine codon in bacteria and archaea requires modification of a C in the anticodon wobble position of the isoleucine tRNA. Here, we report the crystal structure of the archaeal tRNA2(Ile), which contains the modification agmatidine in its anticodon, in complex with the AUA codon on the 70S ribosome. The structure illustrates how agmatidine confers codon specificity for AUA over AUG.

PubMed: 23542153
DOI: 10.1038/NSMB.2545

実験手法

X-RAY DIFFRACTION (3.1 Å)