4V32

Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Thalidomide, Y101F mutant

Summary for 4V32

• Entry DOI: 10.2210/pdb4v32/pdb
• Related: 4V2Y 4V2Z 4V30 4V31
• Descriptor: CEREBLON ISOFORM 4, ZINC ION, S-Thalidomide, ... (4 entities in total)
• Functional Keywords: signaling protein, teratogenicity, aromatic cage
• Biological source: MAGNETOSPIRILLUM GRYPHISWALDENSE
• Total number of polymer chains: 3
• Total formula weight: 42033.64

Authors

Hartmann, M.D.,Lupas, A.N.,Hernandez Alvarez, B. (deposition date: 2014-10-15, release date: 2014-12-17, Last modification date: 2024-05-08)

• Primary citation: Hartmann, M.D.,Boichenko, I.,Coles, M.,Zanini, F.,Lupas, A.N.,Hernandez Alvarez, B.; Thalidomide Mimics Uridine Binding to an Aromatic Cage in Cereblon.; J.Struct.Biol., 188:225-, 2014; PubMed: 25448889; DOI: 10.1016/J.JSB.2014.10.010

Experimental method

X-RAY DIFFRACTION (1.9 Å)