4V1O

Architecture of the RNA polymerase II-Mediator core transcription initiation complex

Summary for 4V1O

• Entry DOI: 10.2210/pdb4v1o/pdb
• Related: 4V1M 4V1N
• EMDB information: 2786
• Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, ... (28 entities in total)
• Functional Keywords: transcription, transcription initiation, rna polymerase ii, general transcription factors
• Biological source: SACCHAROMYCES CEREVISIAE (BAKER'S YEAST); More
• Cellular location: Nucleus: P04050 P38902 P29055 P13393 P41896 P38782 P08518 P38304 Q99278 P32569 P32585 P34162 P32570 P16370 P20433 P20434 P34087 P20436; Nucleus, nucleolus : P22139 P40422 P27999; Cytoplasm : P20435
• Total number of polymer chains: 26
• Total formula weight: 949379.25

Authors

Plaschka, C.,Lariviere, L.,Wenzeck, L.,Hemann, M.,Tegunov, D.,Petrotchenko, E.V.,Borchers, C.H.,Baumeister, W.,Herzog, F.,Villa, E.,Cramer, P. (deposition date: 2014-09-29, release date: 2015-02-04, Last modification date: 2017-08-30)

• Primary citation: Plaschka, C.,Lariviere, L.,Wenzeck, L.,Seizl, M.,Hemann, M.,Tegunov, D.,Petrotchenko, E.V.,Borchers, C.H.,Baumeister, W.,Herzog, F.,Villa, E.,Cramer, P.; Architecture of the RNA Polymerase II-Mediator Core Initiation Complex.; Nature, 518:376-, 2015; PubMed: 25652824; DOI: 10.1038/NATURE14229

Experimental method

ELECTRON MICROSCOPY (9.7 Å)