4UWS
VIM-26-PEG. Leu224 in VIM-26 from Klebsiella pneumoniae has implications for drug binding.
Summary for 4UWS
Entry DOI | 10.2210/pdb4uws/pdb |
Related | 4UWO 4UWP 4UWR |
Descriptor | METALLO-BETA-LACTAMASE VIM-26, SULFATE ION, ZINC ION, ... (6 entities in total) |
Functional Keywords | hydrolase, antibiotic resistance, drug binding site |
Biological source | KLEBSIELLA PNEUMONIAE |
Total number of polymer chains | 1 |
Total formula weight | 28469.45 |
Authors | Leiros, H.-K.S.,Edvardsen, K.S.W.,Bjerga, G.E.K.,Samuelsen, O. (deposition date: 2014-08-14, release date: 2015-02-04, Last modification date: 2024-01-10) |
Primary citation | Leiros, H.S.,Edvardsen, K.S.W.,Bjerga, G.E.K.,Samuelsen, O. Structural and Biochemical Characterization of Vim-26 Show that Leu224 Has Implications for the Substrate Specificity of Vim Metallo-Beta-Lactamases. FEBS J., 282:1031-, 2015 Cited by PubMed: 25601024DOI: 10.1111/FEBS.13200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.66 Å) |
Structure validation
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