4UV4

Crystal structure of anti-FPR Fpro0165 Fab fragment

Summary for 4UV4

Entry DOI	10.2210/pdb4uv4/pdb
Descriptor	FPRO0165 FAB (2 entities in total)
Functional Keywords	immune system, antibody engineering, phage display, long cdr, formyl peptide receptor-1
Biological source	HOMO SAPIENS (HUMAN) More
Total number of polymer chains	2
Total formula weight	49953.84
Authors	Douthwaite, J.A.,Sridharan, S.,Huntington, C.,Marwood, R.,Hammersley, J.,Hakulinen, J.K.,Ek, M.,Sjogren, T.,Rider, D.,Privezentzev, C.,Seaman, J.C.,Cariuk, P.,Knights, V.,Young, J.,Wilkinson, T.,Sleeman, M.,Finch, D.K.,Lowe, D.C.,Vaughan, T.J. (deposition date: 2014-08-04, release date: 2014-12-24, Last modification date: 2024-01-10)
Primary citation	Douthwaite, J.A.,Sridharan, S.,Huntington, C.,Hammersley, J.,Marwood, R.,Hakulinen, J.K.,Ek, M.,Sjogren, T.,Rider, D.,Privezentzev, C.,Seaman, J.C.,Cariuk, P.,Knights, V.,Young, J.,Wilkinson, T.,Sleeman, M.,Finch, D.K.,Lowe, D.C.,Vaughan, T.J. Affinity Maturation of a Novel Antagonistic Human Monoclonal Antibody with a Long Vh Cdr3 Targeting the Class a Gpcr Formyl-Peptide Receptor 1. Mabs, 7:152-, 2015 Cited by PubMed: 25484051 DOI: 10.4161/19420862.2014.985158 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.08 Å)

Structure validation