4UV4

Crystal structure of anti-FPR Fpro0165 Fab fragment

4UV4 の概要

• エントリーDOI: 10.2210/pdb4uv4/pdb
• 分子名称: FPRO0165 FAB (2 entities in total)
• 機能のキーワード: immune system, antibody engineering, phage display, long cdr, formyl peptide receptor-1
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 49953.84

構造登録者

Douthwaite, J.A.,Sridharan, S.,Huntington, C.,Marwood, R.,Hammersley, J.,Hakulinen, J.K.,Ek, M.,Sjogren, T.,Rider, D.,Privezentzev, C.,Seaman, J.C.,Cariuk, P.,Knights, V.,Young, J.,Wilkinson, T.,Sleeman, M.,Finch, D.K.,Lowe, D.C.,Vaughan, T.J. (登録日: 2014-08-04, 公開日: 2014-12-24, 最終更新日: 2024-01-10)

• 主引用文献: Douthwaite, J.A.,Sridharan, S.,Huntington, C.,Hammersley, J.,Marwood, R.,Hakulinen, J.K.,Ek, M.,Sjogren, T.,Rider, D.,Privezentzev, C.,Seaman, J.C.,Cariuk, P.,Knights, V.,Young, J.,Wilkinson, T.,Sleeman, M.,Finch, D.K.,Lowe, D.C.,Vaughan, T.J.; Affinity Maturation of a Novel Antagonistic Human Monoclonal Antibody with a Long Vh Cdr3 Targeting the Class a Gpcr Formyl-Peptide Receptor 1.; Mabs, 7:152-, 2015; PubMed: 25484051; DOI: 10.4161/19420862.2014.985158

実験手法

X-RAY DIFFRACTION (3.08 Å)