4UQJ

Cryo-EM density map of GluA2em in complex with ZK200775

Summary for 4UQJ

Entry DOI	10.2210/pdb4uqj/pdb
Related	4UQ6 4UQK 4UQQ
EMDB information	2680
Descriptor	GLUTAMATE RECEPTOR 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid (2 entities in total)
Functional Keywords	transport protein, glua2em antagonist-bound closed state
Biological source	RATTUS NORVEGICUS (NORWAY RAT)
Cellular location	Cell membrane; Multi-pass membrane protein: P19491
Total number of polymer chains	4
Total formula weight	371731.48
Authors	Meyerson, J.R.,Kumar, J.,Chittori, S.,Rao, P.,Pierson, J.,Bartesaghi, A.,Mayer, M.L.,Subramaniam, S. (deposition date: 2014-06-24, release date: 2014-08-13, Last modification date: 2017-08-02)
Primary citation	Meyerson, J.R.,Kumar, J.,Chittori, S.,Rao, P.,Pierson, J.,Bartesaghi, A.,Mayer, M.L.,Subramaniam, S. Structural Mechanism of Glutamate Receptor Activation and Desensitization Nature, 514:328-, 2014 Cited by PubMed: 25119039 DOI: 10.1038/NATURE13603 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (10.4 Å)

Structure validation