4UP0
Ternary crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a H3K4me2 peptide
Summary for 4UP0
Entry DOI | 10.2210/pdb4up0/pdb |
Descriptor | PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, HISTONE H3.1, ZINC ION, ... (4 entities in total) |
Functional Keywords | transcription, wnt signalling, phd finger, bcl9l, hd1 domain |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Nucleus : Q86UU0 P68431 |
Total number of polymer chains | 2 |
Total formula weight | 12302.37 |
Authors | Miller, T.C.R.,Fiedler, M.,Rutherford, T.J.,Birchall, K.,Chugh, J.,Bienz, M. (deposition date: 2014-06-11, release date: 2014-11-05, Last modification date: 2024-01-10) |
Primary citation | Miller, T.C.R.,Rutherford, T.J.,Birchall, K.,Chugh, J.,Fiedler, M.,Bienz, M. Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger. Acs Chem.Biol., 9:2864-, 2014 Cited by PubMed: 25323450DOI: 10.1021/CB500585S PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.28 Å) |
Structure validation
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