4UNU
MCG - a dimer of lambda variable domains
Summary for 4UNU
Entry DOI | 10.2210/pdb4unu/pdb |
Related | 4UNT 4UNV |
Descriptor | IG LAMBDA CHAIN V-II REGION MGC, POLYETHYLENE GLYCOL (N=34), SULFATE ION, ... (4 entities in total) |
Functional Keywords | immune system, bence-jones, light chains, immunoglobulin, amyloid |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Secreted : P01709 |
Total number of polymer chains | 2 |
Total formula weight | 24949.04 |
Authors | Brumshtein, B.,Esswein, S.R.,Landau, M.,Ryan, C.,Whitelegge, J.,Casio, D.,Sawaya, M.R.,Eisenberg, D.S. (deposition date: 2014-05-30, release date: 2014-08-27, Last modification date: 2024-01-10) |
Primary citation | Brumshtein, B.,Esswein, S.R.,Landau, M.,Ryan, C.M.,Whitelegge, J.P.,Phillips, M.L.,Cascio, D.,Sawaya, M.R.,Eisenberg, D.S. Formation of Amyloid Fibers by Monomeric Light-Chain Variable Domains. J.Biol.Chem., 289:27513-, 2014 Cited by PubMed: 25138218DOI: 10.1074/JBC.M114.585638 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (0.95 Å) |
Structure validation
Download full validation report