4UNU

MCG - a dimer of lambda variable domains

Summary for 4UNU

• Entry DOI: 10.2210/pdb4unu/pdb
• Related: 4UNT 4UNV
• Descriptor: IG LAMBDA CHAIN V-II REGION MGC, POLYETHYLENE GLYCOL (N=34), SULFATE ION, ... (4 entities in total)
• Functional Keywords: immune system, bence-jones, light chains, immunoglobulin, amyloid
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Secreted : P01709
• Total number of polymer chains: 2
• Total formula weight: 24949.04

Authors

Brumshtein, B.,Esswein, S.R.,Landau, M.,Ryan, C.,Whitelegge, J.,Casio, D.,Sawaya, M.R.,Eisenberg, D.S. (deposition date: 2014-05-30, release date: 2014-08-27, Last modification date: 2024-01-10)

• Primary citation: Brumshtein, B.,Esswein, S.R.,Landau, M.,Ryan, C.M.,Whitelegge, J.P.,Phillips, M.L.,Cascio, D.,Sawaya, M.R.,Eisenberg, D.S.; Formation of Amyloid Fibers by Monomeric Light-Chain Variable Domains.; J.Biol.Chem., 289:27513-, 2014; PubMed: 25138218; DOI: 10.1074/JBC.M114.585638

Experimental method

X-RAY DIFFRACTION (0.95 Å)