4UHR
Thermostabilised HUMAN A2a Receptor with CGS21680 bound
Summary for 4UHR
Entry DOI | 10.2210/pdb4uhr/pdb |
Related | 4UG2 |
Descriptor | THERMOSTABILISED HUMAN A2A RECEPTOR, 2-[P-(2-CARBOXYETHYL)PHENYLETHYL-AMINO]-5'-N-ETHYLCARBOXAMIDO ADENOSINE (3 entities in total) |
Functional Keywords | signaling protein, siganling protein, g protein coupled receptor, seven-helix receptor, integral membrane protein, agonist bound form, thermostabilising point mutations, gpcr, 7tm receptor |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 36522.29 |
Authors | Lebon, G.,Edwards, P.C.,Leslie, A.G.W.,Tate, C.G. (deposition date: 2015-03-25, release date: 2015-04-08, Last modification date: 2024-01-10) |
Primary citation | Lebon, G.,Edwards, P.C.,Leslie, A.G.W.,Tate, C.G. Molecular Determinants of Cgs21680 Binding to the Human Adenosine A2A Receptor. Mol.Pharmacol., 87:907-, 2015 Cited by PubMed: 25762024DOI: 10.1124/MOL.114.097360 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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