4UBD
Crystal structure of a neutralizing human monoclonal antibody with 1968 H3 HA
Summary for 4UBD
Entry DOI | 10.2210/pdb4ubd/pdb |
Descriptor | Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, monoclonal antibody H chain, ... (7 entities in total) |
Functional Keywords | hemagglutinin, h3n2, monoclonal antibody, viral protein-immune system complex, viral protein/immune system |
Biological source | Influenza A virus More |
Total number of polymer chains | 24 |
Total formula weight | 625697.69 |
Authors | Shore, D.A.,Yang, H.,Cho, M.,Donis, R.O.,Stevens, J. (deposition date: 2014-08-12, release date: 2015-06-24, Last modification date: 2023-12-27) |
Primary citation | Wu, Y.,Cho, M.,Shore, D.,Song, M.,Choi, J.,Jiang, T.,Deng, Y.Q.,Bourgeois, M.,Almli, L.,Yang, H.,Chen, L.M.,Shi, Y.,Qi, J.,Li, A.,Yi, K.S.,Chang, M.,Bae, J.S.,Lee, H.,Shin, J.,Stevens, J.,Hong, S.,Qin, C.F.,Gao, G.F.,Chang, S.J.,Donis, R.O. A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus. Nat Commun, 6:7708-7708, 2015 Cited by PubMed: 26196962DOI: 10.1038/ncomms8708 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
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