4UAA

CTX-M-14 Class A Beta-Lactamase in Complex with a Non-Covalent Inhibitor at Sub-Angstrom Resolution

Summary for 4UAA

Entry DOI	10.2210/pdb4uaa/pdb
Related	4UA6 4UA7 4UA9
Descriptor	Beta-lactamase CTX-M-14, N-[3-(2H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)-1H-benzimidazole-4-carboxamide, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	ctx-m-14, class a beta-lactamase, non-covalent complex, ultra high resolution, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	57840.08
Authors	Nichols, D.A.,Chen, Y. (deposition date: 2014-08-08, release date: 2015-06-24, Last modification date: 2023-09-27)
Primary citation	Nichols, D.A.,Hargis, J.C.,Sanishvili, R.,Jaishankar, P.,Defrees, K.,Smith, E.W.,Wang, K.K.,Prati, F.,Renslo, A.R.,Woodcock, H.L.,Chen, Y. Ligand-Induced Proton Transfer and Low-Barrier Hydrogen Bond Revealed by X-ray Crystallography. J.Am.Chem.Soc., 137:8086-8095, 2015 Cited by PubMed: 26057252 DOI: 10.1021/jacs.5b00749 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (0.86 Å)

Structure validation