4U86
Human Pin1 with cysteine sulfonic acid 113
Summary for 4U86
Entry DOI | 10.2210/pdb4u86/pdb |
Related | 4U84 4U85 |
Descriptor | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL (3 entities in total) |
Functional Keywords | pin1 oxidation isomerase, isomerase |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus: Q13526 |
Total number of polymer chains | 1 |
Total formula weight | 20510.71 |
Authors | |
Primary citation | Chen, C.H.,Li, W.,Sultana, R.,You, M.H.,Kondo, A.,Shahpasand, K.,Kim, B.M.,Luo, M.L.,Nechama, M.,Lin, Y.M.,Yao, Y.,Lee, T.H.,Zhou, X.Z.,Swomley, A.M.,Allan Butterfield, D.,Zhang, Y.,Lu, K.P. Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease. Neurobiol.Dis., 76:13-23, 2015 Cited by PubMed: 25576397DOI: 10.1016/j.nbd.2014.12.027 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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