4U82

Structure of S. aureus undecaprenyl diphosphate synthase in complex with FSPP and sulfate

4U82 の概要

• エントリーDOI: 10.2210/pdb4u82/pdb
• 分子名称: Isoprenyl transferase, MAGNESIUM ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, ... (5 entities in total)
• 機能のキーワード: alkyl and aryl transferases, anti-bacterial agents, benzoates, biosynthetic pathways, cell wall, diphosphonates, drug discovery, high-throughput screening assays, methicillin, microbial sensitivity tests, pyrrolidinones, staphylococcus aureus, terpenes, transferase
• 由来する生物種: Staphylococcus aureus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 30420.96

構造登録者

Zhu, W.,Oldfield, E. (登録日: 2014-07-31, 公開日: 2015-02-04, 最終更新日: 2023-09-27)

• 主引用文献: Zhu, W.,Wang, Y.,Li, K.,Gao, J.,Huang, C.H.,Chen, C.C.,Ko, T.P.,Zhang, Y.,Guo, R.T.,Oldfield, E.; Antibacterial drug leads: DNA and enzyme multitargeting.; J.Med.Chem., 58:1215-1227, 2015; PubMed: 25574764; DOI: 10.1021/jm501449u

実験手法

X-RAY DIFFRACTION (1.66 Å)