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4U4Q

Crystal structure of Homoharringtonine bound to the yeast 80S ribosome

This is a non-PDB format compatible entry.
Summary for 4U4Q
Entry DOI10.2210/pdb4u4q/pdb
Descriptor18S ribosomal RNA, 40S ribosomal protein S8-A, 40S ribosomal protein S9-A, ... (88 entities in total)
Functional Keywordstranslation, ribosome, 40s, 60s, 80s, eukaryote, rna-protein complex, inhibitor, antibiotic
Biological sourceSaccharomyces cerevisiae ATCC 204508 / S288c
More
Cellular locationCytoplasm : P32905 P33442 P25443 P05750 P0CX35 P26783 P0CX37 P26786 P0CX39 O13516 Q08745 P0CX47 P48589 P05756 P06367 Q01855 P0CX51 P02407 P0CX55 P07280 P38701 P0C0V8 P0C0W1 P0CX29 P0CX31 Q3E792 P39939 P35997 Q3E7X9 P41057 P0CX33 P38011 P39015 P0CX45 P14126 P10664 P26321 Q02326 P05737 P17076 P05738 P41805 Q3E757 Q12690 P36105 P05748 P26784 P05740 P0CX49 P0CX82 P0CX23 Q02753 P05749 P0CX41 P04449 P04456 P05743 P0C2H6 P02406 P05747 P14120 P0C2H8 P38061 P05744 P87262 P0CX84 P05745 P49166 P49167 P04650 P0CX86 P0CX27 P0CX25 P0CX33 P05317
Ubiquitin: Cytoplasm . 40S ribosomal protein S31: Cytoplasm : P05759
Ubiquitin: Cytoplasm . 60S ribosomal protein L40: Cytoplasm: P0CH08
Total number of polymer chains162
Total formula weight6632316.71
Authors
Garreau de Loubresse, N.,Prokhorova, I.,Yusupova, G.,Yusupov, M. (deposition date: 2014-07-24, release date: 2014-10-22, Last modification date: 2023-12-20)
Primary citationGarreau de Loubresse, N.,Prokhorova, I.,Holtkamp, W.,Rodnina, M.V.,Yusupova, G.,Yusupov, M.
Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513:517-522, 2014
Cited by
PubMed: 25209664
DOI: 10.1038/nature13737
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3 Å)
Structure validation

217705

數據於2024-03-27公開中

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