4U4L

Crystal structure of the metallo-beta-lactamase NDM-1 in complex with a bisthiazolidine inhibitor

Summary for 4U4L

• Entry DOI: 10.2210/pdb4u4l/pdb
• Descriptor: Beta-lactamase NDM-1, ZINC ION, (3R,5R,7aS)-5-(sulfanylmethyl)tetrahydro[1,3]thiazolo[4,3-b][1,3]thiazole-3-carboxylic acid, ... (5 entities in total)
• Functional Keywords: hydrolase
• Biological source: Klebsiella pneumoniae
• Cellular location: Periplasm (Potential): C7C422
• Total number of polymer chains: 4
• Total formula weight: 105714.12

Authors

Kosmopoulou, M.,Hinchliffe, P.,Spencer, J. (deposition date: 2014-07-23, release date: 2014-08-20, Last modification date: 2023-12-20)

• Primary citation: Kosmopoulou, M.,Hinchliffe, P.,Spencer, J.; Crystal structure of the metallo-beta-lactamase NDM-1 in complex with a bisthiazolidine inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)