4U3T
Crystal structure of the transpeptidase domain of Neisseria gonorrhoeae penicillin-binding protein 2 derived from the penicillin-resistant strain 6140
Summary for 4U3T
| Entry DOI | 10.2210/pdb4u3t/pdb |
| Related | 3EQU 3EQV |
| Descriptor | Penicillin-binding protein 2 (2 entities in total) |
| Functional Keywords | penicillin-binding protein, transpeptidase domain, peptidoglycan synthesis, antibiotic resistance, hydrolase |
| Biological source | Neisseria gonorrhoeae FA6140 |
| Total number of polymer chains | 2 |
| Total formula weight | 70822.64 |
| Authors | Fedarovich, A.,Davies, C. (deposition date: 2014-07-22, release date: 2014-12-03, Last modification date: 2023-09-27) |
| Primary citation | Fedarovich, A.,Cook, E.,Tomberg, J.,Nicholas, R.A.,Davies, C. Structural Effect of the Asp345a Insertion in Penicillin-Binding Protein 2 from Penicillin-Resistant Strains of Neisseria gonorrhoeae. Biochemistry, 53:7596-7603, 2014 Cited by PubMed: 25403720DOI: 10.1021/bi5011317 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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