4U2U
Bak domain swapped dimer induced by BidBH3 with CHAPS
Summary for 4U2U
Entry DOI | 10.2210/pdb4u2u/pdb |
Related | 4U2V |
Descriptor | Bcl-2 homologous antagonist/killer (2 entities in total) |
Functional Keywords | apoptosis, bak, bcl-2 |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 37960.54 |
Authors | Brouwer, J.M.,Colman, P.M.,Czabotar, P.E. (deposition date: 2014-07-18, release date: 2014-09-10, Last modification date: 2023-09-27) |
Primary citation | Brouwer, J.M.,Westphal, D.,Dewson, G.,Robin, A.Y.,Uren, R.T.,Bartolo, R.,Thompson, G.V.,Colman, P.M.,Kluck, R.M.,Czabotar, P.E. Bak Core and Latch Domains Separate during Activation, and Freed Core Domains Form Symmetric Homodimers. Mol.Cell, 55:938-946, 2014 Cited by PubMed: 25175025DOI: 10.1016/j.molcel.2014.07.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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