4TYA
An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline
Summary for 4TYA
Entry DOI | 10.2210/pdb4tya/pdb |
Related | 4TXF 4TXS 4TY8 4TY9 4TYB |
Descriptor | Polyprotein, 4-(trifluoromethyl)benzoic acid (2 entities in total) |
Functional Keywords | inhibitor, ns5b, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Hepatitis C virus |
Total number of polymer chains | 4 |
Total formula weight | 251928.41 |
Authors | |
Primary citation | Chen, X.,Qin, S.,Chen, S.,Li, J.,Li, L.,Wang, Z.,Wang, Q.,Lin, J.,Yang, C.,Shui, W. A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline Sci Rep, 5:8361-8361, 2015 Cited by PubMed: 25666181DOI: 10.1038/srep08361 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.94 Å) |
Structure validation
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