4TWC

2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4- carboxamide derivatives as potent inhibitors of CK1d/e

Summary for 4TWC

• Entry DOI: 10.2210/pdb4twc/pdb
• Descriptor: Casein kinase I isoform delta, SULFATE ION, GLYCEROL, ... (7 entities in total)
• Functional Keywords: ck1d, ck1e, phosphorylation, small molecule inhibitor, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 71359.66

Authors

Bischof, J.,Leban, L.,Zaja, M.,Grothey, A.,Radunsky, B.,Othersen, O.,Strobl, S.,Vitt, D.,Knippschild, U. (deposition date: 2014-06-30, release date: 2014-10-08, Last modification date: 2023-12-20)

• Primary citation: Bischof, J.,Leban, J.,Zaja, M.,Grothey, A.,Radunsky, B.,Othersen, O.,Strobl, S.,Vitt, D.,Knippschild, U.; 2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4-carboxamide derivatives as potent inhibitors of CK1d/e.; Amino Acids, 43:1577-1591, 2012; PubMed: 22331384; DOI: 10.1007/s00726-012-1234-x

Experimental method

X-RAY DIFFRACTION (1.7 Å)