4TWC

2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4- carboxamide derivatives as potent inhibitors of CK1d/e

4TWC の概要

• エントリーDOI: 10.2210/pdb4twc/pdb
• 分子名称: Casein kinase I isoform delta, SULFATE ION, GLYCEROL, ... (7 entities in total)
• 機能のキーワード: ck1d, ck1e, phosphorylation, small molecule inhibitor, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 71359.66

構造登録者

Bischof, J.,Leban, L.,Zaja, M.,Grothey, A.,Radunsky, B.,Othersen, O.,Strobl, S.,Vitt, D.,Knippschild, U. (登録日: 2014-06-30, 公開日: 2014-10-08, 最終更新日: 2023-12-20)

• 主引用文献: Bischof, J.,Leban, J.,Zaja, M.,Grothey, A.,Radunsky, B.,Othersen, O.,Strobl, S.,Vitt, D.,Knippschild, U.; 2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4-carboxamide derivatives as potent inhibitors of CK1d/e.; Amino Acids, 43:1577-1591, 2012; PubMed: 22331384; DOI: 10.1007/s00726-012-1234-x

実験手法

X-RAY DIFFRACTION (1.7 Å)