4TWA
Crystal Structure of Prolyl-tRNA Synthetase (PRS) from Plasmodium falciparum
Summary for 4TWA
Entry DOI | 10.2210/pdb4twa/pdb |
Descriptor | Proline--tRNA ligase, CHLORIDE ION, SULFATE ION, ... (4 entities in total) |
Functional Keywords | protein translation, halofuginone, malaria, inhibitor, prs, synthetase, ligase |
Biological source | Plasmodium falciparum |
Cellular location | Cytoplasm : Q8I5R7 |
Total number of polymer chains | 2 |
Total formula weight | 116871.79 |
Authors | Jain, V.,Yogavel, M.,Sharma, A. (deposition date: 2014-06-30, release date: 2014-08-13, Last modification date: 2023-09-27) |
Primary citation | Jain, V.,Kikuchi, H.,Oshima, Y.,Sharma, A.,Yogavel, M. Structural and functional analysis of the anti-malarial drug target prolyl-tRNA synthetase. J. Struct. Funct. Genomics, 15:181-190, 2014 Cited by PubMed: 25047712DOI: 10.1007/s10969-014-9186-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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