4TTI

Crystal structure of double mutant E. Coli purine nucleoside phosphorylase with 4 FMC molecules

4TTI の概要

• エントリーDOI: 10.2210/pdb4tti/pdb
• 分子名称: Purine nucleoside phosphorylase DeoD-type, (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, PHOSPHATE ION, ... (5 entities in total)
• 機能のキーワード: purine nucleoside phosphorylase, formicyn a, transferase
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 155668.15

構造登録者

Stefanic, Z.,Bzowska, A. (登録日: 2014-06-21, 公開日: 2015-07-08, 最終更新日: 2023-12-20)

• 主引用文献: Stefanic, Z.,Narczyk, M.,Mikleusevic, G.,Kazazic, S.,Bzowska, A.,Luic, M.; Crystallographic snapshots of ligand binding to hexameric purine nucleoside phosphorylase and kinetic studies give insight into the mechanism of catalysis.; Sci Rep, 8:15427-15427, 2018; PubMed: 30337572; DOI: 10.1038/s41598-018-33723-1

実験手法

X-RAY DIFFRACTION (1.89 Å)