Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4TLK

Crystal Structure of Human Transthyretin Ser85Pro/Glu92Pro Mutant

Summary for 4TLK
Entry DOI10.2210/pdb4tlk/pdb
Related4TKW 4TL4 4TL5 4TLS
DescriptorTransthyretin, SODIUM ION, GLYCEROL, ... (5 entities in total)
Functional Keywordshuman transthyretin, amyloid, transthyretin, mutant, transport protein
Biological sourceHomo sapiens (Human)
Cellular locationSecreted: P02766
Total number of polymer chains2
Total formula weight28145.53
Authors
Saelices, L.,Cascio, D.,Sawaya, M.,Eisenberg, D.S. (deposition date: 2014-05-30, release date: 2015-10-21, Last modification date: 2023-12-27)
Primary citationSaelices, L.,Johnson, L.M.,Liang, W.Y.,Sawaya, M.R.,Cascio, D.,Ruchala, P.,Whitelegge, J.,Jiang, L.,Riek, R.,Eisenberg, D.S.
Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290:28932-28943, 2015
Cited by
PubMed: 26459562
DOI: 10.1074/jbc.M115.659912
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.44 Å)
Structure validation

217705

数据于2024-03-27公开中

PDB statisticsPDBj update infoContact PDBjnumon