4TKX

Structure of Protease

Summary for 4TKX

Entry DOI	10.2210/pdb4tkx/pdb
Related PRD ID	PRD_000459
Descriptor	Lys-gingipain W83, SULFATE ION, SODIUM ION, ... (9 entities in total)
Functional Keywords	cysteine protease, gingivalis, kgp, co-valent inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Porphyromonas gingivalis
Cellular location	Lys-gingipain catalytic subunit: Secreted, extracellular space . 39 kDa adhesin: Secreted, extracellular space . 15 kDa adhesin: Secreted, extracellular space . 44 kDa adhesin: Secreted, extracellular space : Q51817
Total number of polymer chains	1
Total formula weight	51589.74
Authors	Gorman, M.A.,Parker, M.W. (deposition date: 2014-05-28, release date: 2014-12-31, Last modification date: 2023-12-27)
Primary citation	Gorman, M.A.,Seers, C.A.,Michell, B.J.,Feil, S.C.,Huq, N.L.,Cross, K.J.,Reynolds, E.C.,Parker, M.W. Structure of the lysine specific protease Kgp from Porphyromonas gingivalis, a target for improved oral health. Protein Sci., 24:162-166, 2015 Cited by PubMed: 25327141 DOI: 10.1002/pro.2589 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation