4TKS

Native-SAD phasing for human EGFR kinase domain.

Summary for 4TKS

Entry DOI	10.2210/pdb4tks/pdb
Descriptor	Epidermal growth factor receptor (1 entity in total)
Functional Keywords	egfr kinase domain, native-sad phasing, multiple crystals, low energy, transferase
Biological source	Homo sapiens (Human)
Cellular location	Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted: P00533
Total number of polymer chains	1
Total formula weight	37707.58
Authors	Cai, Z.,Greene, M.I.,Liu, Q. (deposition date: 2014-05-27, release date: 2014-10-08, Last modification date: 2023-12-27)
Primary citation	Liu, Q.,Guo, Y.,Chang, Y.,Cai, Z.,Assur, Z.,Mancia, F.,Greene, M.I.,Hendrickson, W.A. Multi-crystal native SAD analysis at 6 keV. Acta Crystallogr.,Sect.D, 70:2544-2557, 2014 Cited by PubMed: 25286840 DOI: 10.1107/S1399004714013376 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2017 Å)

Structure validation