4SKN
A NUCLEOTIDE-FLIPPING MECHANISM FROM THE STRUCTURE OF HUMAN URACIL-DNA GLYCOSYLASE BOUND TO DNA
Summary for 4SKN
Entry DOI | 10.2210/pdb4skn/pdb |
Descriptor | DNA (5'-D(*TP*GP*GP*GP*(D1P)P*GP*GP*CP*TP*T)-3'), DNA (5'-D(*AP*AP*AP*GP*CP*CP*GP*CP*CP*C)-3'), PROTEIN (URACIL-DNA GLYCOSYLASE), ... (5 entities in total) |
Functional Keywords | dna glycosylase, dna base excision repair, uracil, dna, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 1: Mitochondrion. Isoform 2: Nucleus: P13051 |
Total number of polymer chains | 3 |
Total formula weight | 31697.19 |
Authors | Slupphaug, G.,Mol, C.D.,Kavli, B.,Arvai, A.S.,Krokan, H.E.,Tainer, J.A. (deposition date: 1999-02-20, release date: 1999-02-26, Last modification date: 2023-09-20) |
Primary citation | Slupphaug, G.,Mol, C.D.,Kavli, B.,Arvai, A.S.,Krokan, H.E.,Tainer, J.A. A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA. Nature, 384:87-92, 1996 Cited by PubMed: 8900285DOI: 10.1038/384087a0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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