4S3G

Structure of the F249X mutant of Phosphatidylinositol-specific phospholipase C from Staphylococcus aureus

Summary for 4S3G

• Entry DOI: 10.2210/pdb4s3g/pdb
• Related: 4RV3
• Descriptor: 1-phosphatidylinositol phosphodiesterase, 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, ACETATE ION, ... (4 entities in total)
• Functional Keywords: tim barrel, cation-pi, phospholipase, lyase
• Biological source: Staphylococcus aureus str. Newman
• Cellular location: Secreted: P45723
• Total number of polymer chains: 1
• Total formula weight: 34500.15

Authors

He, T.,Gershenson, A.,Eyles, S.J.,Gao, J.,Roberts, M.F. (deposition date: 2015-01-26, release date: 2015-07-01, Last modification date: 2015-08-19)

• Primary citation: He, T.,Gershenson, A.,Eyles, S.J.,Lee, Y.J.,Liu, W.R.,Wang, J.,Gao, J.,Roberts, M.F.; Fluorinated Aromatic Amino Acids Distinguish Cation-pi Interactions from Membrane Insertion.; J.Biol.Chem., 290:19334-19342, 2015; PubMed: 26092728; DOI: 10.1074/jbc.M115.668343

Experimental method

X-RAY DIFFRACTION (2.5 Å)