4S3F
IspG in complex with Inhibitor 8 (compound 1077)
Summary for 4S3F
Entry DOI | 10.2210/pdb4s3f/pdb |
Related | 2Y0F 3NOY 4G9P 4S38 4S39 4S3A 4S3B 4S3C 4S3D 4S3E |
Descriptor | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, FE3-S4 CLUSTER, but-3-yn-1-yl trihydrogen diphosphate, ... (4 entities in total) |
Functional Keywords | methylerythritol-phosphate pathway, terpene biosynthesis, iron-sulfur enzymes, reaction mechanisms, drug development, oxidoreductase |
Biological source | Thermus thermophilus HB8 |
Total number of polymer chains | 1 |
Total formula weight | 44803.87 |
Authors | Quitterer, F.,Frank, A.,Wang, K.,Rao, G.,O'Dowd, B.,Li, J.,Guerra, F.,Abdel-Azeim, S.,Bacher, A.,Eppinger, J.,Oldfield, E.,Groll, M. (deposition date: 2015-01-26, release date: 2015-04-29, Last modification date: 2023-12-06) |
Primary citation | Quitterer, F.,Frank, A.,Wang, K.,Rao, G.,O'Dowd, B.,Li, J.,Guerra, F.,Abdel-Azeim, S.,Bacher, A.,Eppinger, J.,Oldfield, E.,Groll, M. Atomic-Resolution Structures of Discrete Stages on the Reaction Coordinate of the [Fe4S4] Enzyme IspG (GcpE). J.Mol.Biol., 427:2220-2228, 2015 Cited by PubMed: 25868383DOI: 10.1016/j.jmb.2015.04.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
Download full validation report