4RZC
Fv M6P-1 in complex with mannose-6-phosphate
Summary for 4RZC
Entry DOI | 10.2210/pdb4rzc/pdb |
Descriptor | Fv M6P-1 light chain, Fv M6P-1 heavy chain, 6-O-phosphono-alpha-D-mannopyranose, ... (5 entities in total) |
Functional Keywords | antibody variable fragment, mannose-6-phosphate, immune system |
Biological source | Oryctolagus cuniculus More |
Total number of polymer chains | 8 |
Total formula weight | 100538.63 |
Authors | Blackler, R.J.,Evans, D.W.,Evans, S.V.,Muller-Loennies, S. (deposition date: 2014-12-19, release date: 2015-11-04, Last modification date: 2020-07-29) |
Primary citation | Blackler, R.J.,Evans, D.W.,Smith, D.F.,Cummings, R.D.,Brooks, C.L.,Braulke, T.,Liu, X.,Evans, S.V.,Muller-Loennies, S. Single-chain antibody-fragment M6P-1 possesses a mannose 6-phosphate monosaccharide-specific binding pocket that distinguishes N-glycan phosphorylation in a branch-specific manner. Glycobiology, 26:181-192, 2016 Cited by PubMed: 26503547DOI: 10.1093/glycob/cwv093 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.723 Å) |
Structure validation
Download full validation report