4RZC

Fv M6P-1 in complex with mannose-6-phosphate

Summary for 4RZC

• Entry DOI: 10.2210/pdb4rzc/pdb
• Descriptor: Fv M6P-1 light chain, Fv M6P-1 heavy chain, 6-O-phosphono-alpha-D-mannopyranose, ... (5 entities in total)
• Functional Keywords: antibody variable fragment, mannose-6-phosphate, immune system
• Biological source: Oryctolagus cuniculus; More
• Total number of polymer chains: 8
• Total formula weight: 100538.63

Authors

Blackler, R.J.,Evans, D.W.,Evans, S.V.,Muller-Loennies, S. (deposition date: 2014-12-19, release date: 2015-11-04, Last modification date: 2020-07-29)

• Primary citation: Blackler, R.J.,Evans, D.W.,Smith, D.F.,Cummings, R.D.,Brooks, C.L.,Braulke, T.,Liu, X.,Evans, S.V.,Muller-Loennies, S.; Single-chain antibody-fragment M6P-1 possesses a mannose 6-phosphate monosaccharide-specific binding pocket that distinguishes N-glycan phosphorylation in a branch-specific manner.; Glycobiology, 26:181-192, 2016; PubMed: 26503547; DOI: 10.1093/glycob/cwv093

Experimental method

X-RAY DIFFRACTION (2.723 Å)