4RZC

Fv M6P-1 in complex with mannose-6-phosphate

4RZC の概要

• エントリーDOI: 10.2210/pdb4rzc/pdb
• 分子名称: Fv M6P-1 light chain, Fv M6P-1 heavy chain, 6-O-phosphono-alpha-D-mannopyranose, ... (5 entities in total)
• 機能のキーワード: antibody variable fragment, mannose-6-phosphate, immune system
• 由来する生物種: Oryctolagus cuniculus; 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 100538.63

構造登録者

Blackler, R.J.,Evans, D.W.,Evans, S.V.,Muller-Loennies, S. (登録日: 2014-12-19, 公開日: 2015-11-04, 最終更新日: 2020-07-29)

• 主引用文献: Blackler, R.J.,Evans, D.W.,Smith, D.F.,Cummings, R.D.,Brooks, C.L.,Braulke, T.,Liu, X.,Evans, S.V.,Muller-Loennies, S.; Single-chain antibody-fragment M6P-1 possesses a mannose 6-phosphate monosaccharide-specific binding pocket that distinguishes N-glycan phosphorylation in a branch-specific manner.; Glycobiology, 26:181-192, 2016; PubMed: 26503547; DOI: 10.1093/glycob/cwv093

実験手法

X-RAY DIFFRACTION (2.723 Å)