4RWA

Synchrotron structure of the human delta opioid receptor in complex with a bifunctional peptide (PSI community target)

4RWA の概要

• エントリーDOI: 10.2210/pdb4rwa/pdb
• 関連するPDBエントリー: 4EJ4 4N6H 4RWD
• 関連するBIRD辞書のPRD_ID: PRD_001256
• 分子名称: Soluble cytochrome b562,Delta-type opioid receptor, bifunctional peptide, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ... (4 entities in total)
• 機能のキーワード: human opioid receptor, bifunctional peptide, gpcr signaling, gpcr network, membrane protein, psi-biology, structural genomics, gpcr, membrane, lipidic cubic phase, bril
• 由来する生物種: Escherichia coli; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 92951.73

構造登録者

Fenalti, G.,Zatsepin, N.A.,Betti, C.,Giguere, P.,Han, G.W.,Ishchenko, A.,Liu, W.,Guillemyn, K.,Zhang, H.,James, D.,Wang, D.,Weierstall, U.,Spence, J.C.H.,Boutet, S.,Messerschmidt, M.,Williams, G.J.,Gati, C.,Yefanov, O.M.,White, T.A.,Oberthuer, D.,Metz, M.,Yoon, C.H.,Barty, A.,Chapman, H.N.,Basu, S.,Coe, J.,Conrad, C.E.,Fromme, R.,Fromme, P.,Tourwe, D.,Schiller, P.W.,Roth, B.L.,Ballet, S.,Katritch, V.,Stevens, R.C.,Cherezov, V.,GPCR Network (GPCR) (登録日: 2014-12-01, 公開日: 2015-01-14, 最終更新日: 2023-12-06)

• 主引用文献: Fenalti, G.,Zatsepin, N.A.,Betti, C.,Giguere, P.,Han, G.W.,Ishchenko, A.,Liu, W.,Guillemyn, K.,Zhang, H.,James, D.,Wang, D.,Weierstall, U.,Spence, J.C.,Boutet, S.,Messerschmidt, M.,Williams, G.J.,Gati, C.,Yefanov, O.M.,White, T.A.,Oberthuer, D.,Metz, M.,Yoon, C.H.,Barty, A.,Chapman, H.N.,Basu, S.,Coe, J.,Conrad, C.E.,Fromme, R.,Fromme, P.,Tourwe, D.,Schiller, P.W.,Roth, B.L.,Ballet, S.,Katritch, V.,Stevens, R.C.,Cherezov, V.; Structural basis for bifunctional peptide recognition at human delta-opioid receptor.; Nat.Struct.Mol.Biol., 22:265-268, 2015; PubMed: 25686086; DOI: 10.1038/nsmb.2965

実験手法

X-RAY DIFFRACTION (3.28 Å)