4RUA
Crystal structure of Y-family DNA polymerase Dpo4 bypassing a MeFapy-dG adduct
Summary for 4RUA
Entry DOI | 10.2210/pdb4rua/pdb |
Related | 4RU9 4RUC |
Descriptor | DNA polymerase IV, Nucleic acids Template: TCAT(MF7)GAATCCTTCCCCC, Nucleic acids Primar: GGGGGAAGGATTC, ... (6 entities in total) |
Functional Keywords | protein, dna, dna damage, dna-directed dna polymerase, adenosine triphosphate, y-family polymerase, trans-lesion synthesis (tls), dna binding, mefapy-dg lesion bypass, 2, 6-diamino-4-hydroxy n(5)-(methyl)-formamidopyrimidine (mefapy-dg) lesion, transferase-dna complex, transferase/dna |
Biological source | Sulfolobus solfataricus P2 More |
Cellular location | Cytoplasm : Q97W02 |
Total number of polymer chains | 3 |
Total formula weight | 49147.14 |
Authors | Patra, A.,Banerjee, S.,Stone, M.P.,Egli, M. (deposition date: 2014-11-18, release date: 2015-08-05, Last modification date: 2023-09-20) |
Primary citation | Patra, A.,Banerjee, S.,Johnson Salyard, T.L.,Malik, C.K.,Christov, P.P.,Rizzo, C.J.,Stone, M.P.,Egli, M. Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase eta and Sulfolobus solfataricus P2 Polymerase IV. J.Am.Chem.Soc., 137:7011-7014, 2015 Cited by PubMed: 25988947DOI: 10.1021/jacs.5b02701 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.07 Å) |
Structure validation
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