4RTO

Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with Sinefungin and with DNA Containing Proximal Pap Regulon Sequence

4RTO の概要

• エントリーDOI: 10.2210/pdb4rto/pdb
• 関連するPDBエントリー: 2G1P 2ORE 4RTJ 4RTK 4RTL 4RTM 4RTN 4RTP 4RTQ 4RTR 4RTS
• 分子名称: DNA adenine methylase, DNA (5'-D(*TP*TP*TP*AP*AP*AP*GP*AP*TP*CP*G)-3'), DNA (5'-D(*AP*CP*GP*AP*TP*CP*TP*TP*TP*AP*A)-3'), ... (5 entities in total)
• 機能のキーワード: dam methylation, gatc recognition, base flipping, bacterial virulence, methylation-independent transcriptional repressor, transferase-dna complex, transferase/dna
• 由来する生物種: Escherichia coli; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 41416.79

構造登録者

Horton, J.R.,Cheng, X. (登録日: 2014-11-15, 公開日: 2015-04-15, 最終更新日: 2023-09-20)

• 主引用文献: Horton, J.R.,Zhang, X.,Blumenthal, R.M.,Cheng, X.; Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.; Nucleic Acids Res., 43:4296-4308, 2015; PubMed: 25845600; DOI: 10.1093/nar/gkv251

実験手法

X-RAY DIFFRACTION (2.69 Å)