4RS3

Crystal structure of carbohydrate transporter A0QYB3 from Mycobacterium smegmatis str. MC2 155, target EFI-510969, in complex with xylitol

4RS3 の概要

• エントリーDOI: 10.2210/pdb4rs3/pdb
• 分子名称: ABC transporter, carbohydrate uptake transporter-2 (CUT2) family, periplasmic sugar-binding protein, Xylitol, ZINC ION, ... (7 entities in total)
• 機能のキーワード: sugar transporter, abc-type, enzyme function initiative, efi, structural genomics, transport protein, hydrolase
• 由来する生物種: Mycobacterium smegmatis str. MC2 155
• 細胞内の位置: Cell membrane ; Lipid-anchor : A0QYB3
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36556.72

構造登録者

Patskovsky, Y.,Toro, R.,Bhosle, R.,Al Obaidi, N.,Morisco, L.L.,Wasserman, S.R.,Chamala, S.,Attonito, J.D.,Scott Glenn, A.,Chowdhury, S.,Lafleur, J.,Hillerich, B.,Siedel, R.D.,Love, J.,Whalen, K.L.,Gerlt, J.A.,Almo, S.C.,Enzyme Function Initiative (EFI) (登録日: 2014-11-06, 公開日: 2014-11-19, 最終更新日: 2020-07-29)

• 主引用文献: Huang, H.,Carter, M.S.,Vetting, M.W.,Al-Obaidi, N.,Patskovsky, Y.,Almo, S.C.,Gerlt, J.A.; A General Strategy for the Discovery of Metabolic Pathways: d-Threitol, l-Threitol, and Erythritol Utilization in Mycobacterium smegmatis.; J.Am.Chem.Soc., 137:14570-14573, 2015; PubMed: 26560079; DOI: 10.1021/jacs.5b08968

実験手法

X-RAY DIFFRACTION (1.4 Å)