4RRR

K121M mutant of N-terminal editing domain of threonyl-tRNA synthetase from Pyrococcus abyssi with L-Thr3AA

Summary for 4RRR

Related4RR6 4RR7 4RR8 4RR9 4RRA 4RRB 4RRC 4RRD 4RRF 4RRG 4RRH 4RRI 4RRJ 4RRK 4RRL 4RRM 4RRQ
DescriptorThreonine--tRNA ligase, 3'-deoxy-3'-(L-threonylamino)adenosine (3 entities in total)
Functional Keywordsdtd-like fold, proofreading, ligase
Biological sourcePyrococcus abyssi GE5
Cellular locationCytoplasm  Q9UZ14
Total number of polymer chains2
Total molecular weight34215.38
Authors
Hussain, T.,Kamarthapu, V.,Sankaranarayanan, R. (deposition date: 2014-11-06, release date: 2015-07-15, Last modification date: 2017-11-22)
Primary citation
Ahmad, S.,Muthukumar, S.,Kuncha, S.K.,Routh, S.B.,Yerabham, A.S.,Hussain, T.,Kamarthapu, V.,Kruparani, S.P.,Sankaranarayanan, R.
Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6:7552-7552, 2015
PubMed: 26113036 (PDB entries with the same primary citation)
DOI: 10.1038/ncomms8552
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.86 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.235900.8%2.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report