4RPX
Precatalytic ternary complex of Human DNA Polymerase Beta With Gapped DNA Containing an 8-oxo-7,8-dihydro-Guanine (8-oxoG) and dCTP in the presence of CaCl2
Summary for 4RPX
Entry DOI | 10.2210/pdb4rpx/pdb |
Related | 4RPY 4RPZ 4RQ0 4RQ1 4RQ2 4RQ3 4RQ4 4RQ5 4RQ6 4RQ7 4RQ8 |
Descriptor | DNA polymerase beta, DNA (5'-D(P*GP*TP*CP*GP*G)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ... (10 entities in total) |
Functional Keywords | x-family, pol beta, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P06746 |
Total number of polymer chains | 4 |
Total formula weight | 50199.87 |
Authors | |
Primary citation | Vyas, R.,Reed, A.J.,Tokarsky, E.J.,Suo, Z. Viewing Human DNA Polymerase beta Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent Crystallography. J.Am.Chem.Soc., 137:5225-5230, 2015 Cited by PubMed: 25825995DOI: 10.1021/jacs.5b02109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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