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5DZD

Crystal Structure of WW4 domain of ITCH in complex with TXNIP peptide

Replaces:  4ROI
Summary for 5DZD
Entry DOI10.2210/pdb5dzd/pdb
DescriptorE3 ubiquitin-protein ligase Itchy homolog, Thioredoxin-interacting protein, UNKNOWN ATOM OR ION, ... (4 entities in total)
Functional Keywordsstructural genomics, structural genomics consortium, sgc, ligase-protein binding complex, ligase/protein binding
Biological sourceHomo sapiens (Human)
More
Cellular locationCell membrane ; Peripheral membrane protein ; Cytoplasmic side : Q96J02
Cytoplasm : Q9H3M7
Total number of polymer chains4
Total formula weight13725.48
Authors
Liu, Y.,Tempel, W.,Dong, A.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2015-09-25, release date: 2015-10-14, Last modification date: 2023-09-27)
Primary citationLiu, Y.,Tempel, W.,Dong, A.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.
Crystal Structure of WW4 domain of ITCH in complex with TXNIP peptide
To be Published,
Experimental method
Structure validation

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