4RNR

Crystal structure of broadly neutralizing anti-HIV antibody PGT130

4RNR の概要

• エントリーDOI: 10.2210/pdb4rnr/pdb
• 分子名称: PGT130 Heavy Chain, PGT130 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: pgt130, pgt 130, immunoglobulin fold, broadly neutralizing antibody, hiv-1 gp120 binding, n-linked glycan, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 97082.40

構造登録者

Kong, L.,Wilson, I.A. (登録日: 2014-10-24, 公開日: 2014-11-19, 最終更新日: 2020-07-29)

• 主引用文献: Doores, K.J.,Kong, L.,Krumm, S.A.,Le, K.M.,Sok, D.,Laserson, U.,Garces, F.,Poignard, P.,Wilson, I.A.,Burton, D.R.; Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope.; J.Virol., 89:1105-1118, 2015; PubMed: 25378488; DOI: 10.1128/JVI.02905-14

実験手法

X-RAY DIFFRACTION (2.758 Å)