4RKX

Identification and characterization of a small molecule inhibitor of S. pyogenes SpeB.

Summary for 4RKX

Entry DOI	10.2210/pdb4rkx/pdb
Related	4d8b 4D8e 4d8i
Descriptor	Streptopain, NITRATE ION, benzyl (cyanomethyl)carbamate, ... (4 entities in total)
Functional Keywords	papain fold, cysteine protease, secreted, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Streptococcus pyogenes
Total number of polymer chains	1
Total formula weight	28933.90
Authors	Wang, A.Y.,Gonzalez-Paez, G.E.,Wolan, D.W. (deposition date: 2014-10-14, release date: 2015-07-22, Last modification date: 2023-09-20)
Primary citation	Wang, A.Y.,Gonzalez-Paez, G.E.,Wolan, D.W. Identification and Co-complex Structure of a New S. pyogenes SpeB Small Molecule Inhibitor. Biochemistry, 54:4365-4373, 2015 Cited by PubMed: 26132413 DOI: 10.1021/acs.biochem.5b00607 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.59 Å)

Structure validation