4RKG

Structure of the MSL2 CXC domain bound with a non-specific (GC)6 DNA

Summary for 4RKG

• Entry DOI: 10.2210/pdb4rkg/pdb
• Related: 4RKH
• Descriptor: E3 ubiquitin-protein ligase msl-2, DNA (5'-D(*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*C)-3'), ZINC ION (3 entities in total)
• Functional Keywords: zinc cluster, dna binding domain, dosage compensation, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Drosophila melanogaster (Fruit fly)
• Cellular location: Nucleus: P50534
• Total number of polymer chains: 4
• Total formula weight: 19224.42

Authors

Zheng, S.,Ye, K. (deposition date: 2014-10-13, release date: 2015-01-21)

• Primary citation: Zheng, S.,Villa, R.,Wang, J.,Feng, Y.,Wang, J.,Becker, P.B.,Ye, K.; Structural basis of X chromosome DNA recognition by the MSL2 CXC domain during Drosophila dosage compensation.; Genes Dev., 28:2652-2662, 2014; PubMed: 25452275; DOI: 10.1101/gad.250936.114

Experimental method

X-RAY DIFFRACTION (2.5 Å)