4RJY
Crystal structure of E. coli L-Threonine Aldolase in complex with a non-covalently uncleaved bound L-serine substrate
Summary for 4RJY
Entry DOI | 10.2210/pdb4rjy/pdb |
Descriptor | Low specificity L-threonine aldolase, SODIUM ION, SERINE, ... (4 entities in total) |
Functional Keywords | pyridoxal-5-phosphate, threonine aldolase, aldimine, catalytic mechanism, retro-aldol cleavage, plp-dependent enzymes, lyase |
Biological source | Escherichia coli |
Total number of polymer chains | 4 |
Total formula weight | 147585.84 |
Authors | Safo, M.K.,Chowdhury, N.,Gandhi, A.K. (deposition date: 2014-10-11, release date: 2014-10-29, Last modification date: 2015-02-04) |
Primary citation | Remesh, S.G.,Ghatge, M.S.,Ahmed, M.H.,Musayev, F.N.,Gandhi, A.,Chowdhury, N.,di Salvo, M.L.,Kellogg, G.E.,Contestabile, R.,Schirch, V.,Safo, M.K. Molecular basis of E. colil-threonine aldolase catalytic inactivation at low pH. Biochim.Biophys.Acta, 1854:278-283, 2015 Cited by PubMed: 25560296DOI: 10.1016/j.bbapap.2014.12.023 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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