4RJY

Crystal structure of E. coli L-Threonine Aldolase in complex with a non-covalently uncleaved bound L-serine substrate

4RJY の概要

• エントリーDOI: 10.2210/pdb4rjy/pdb
• 分子名称: Low specificity L-threonine aldolase, SODIUM ION, SERINE, ... (4 entities in total)
• 機能のキーワード: pyridoxal-5-phosphate, threonine aldolase, aldimine, catalytic mechanism, retro-aldol cleavage, plp-dependent enzymes, lyase
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 147585.84

構造登録者

Safo, M.K.,Chowdhury, N.,Gandhi, A.K. (登録日: 2014-10-11, 公開日: 2014-10-29, 最終更新日: 2015-02-04)

• 主引用文献: Remesh, S.G.,Ghatge, M.S.,Ahmed, M.H.,Musayev, F.N.,Gandhi, A.,Chowdhury, N.,di Salvo, M.L.,Kellogg, G.E.,Contestabile, R.,Schirch, V.,Safo, M.K.; Molecular basis of E. colil-threonine aldolase catalytic inactivation at low pH.; Biochim.Biophys.Acta, 1854:278-283, 2015; PubMed: 25560296; DOI: 10.1016/j.bbapap.2014.12.023

実験手法

X-RAY DIFFRACTION (2.1 Å)