4RHP

Crystal structure of human COQ9 in complex with a phospholipid, Northeast Structural Genomics Consortium Target HR5043

Summary for 4RHP

Entry DOI	10.2210/pdb4rhp/pdb
Descriptor	Ubiquinone biosynthesis protein COQ9, mitochondrial, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE (3 entities in total)
Functional Keywords	structural genomics, psi-biology, northeast structural genomics consortium, nesg, all alpha-helical protein, ubiquinone biosynthesis, mitochondrial, mitochondrial protein partnership, mpp, biosynthetic protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	54875.46
Authors	Forouhar, F.,Lew, S.,Seetharaman, J.,Wang, H.,Lee, D.,Kogan, S.,Maglaqui, M.,Xiao, R.,Everett, J.K.,Montelione, G.T.,Hunt, J.F.,Tong, L.,Northeast Structural Genomics Consortium (NESG),Mitochondrial Protein Partnership (MPP) (deposition date: 2014-10-02, release date: 2014-10-22, Last modification date: 2019-08-14)
Primary citation	Lohman, D.C.,Forouhar, F.,Beebe, E.T.,Stefely, M.S.,Minogue, C.E.,Ulbrich, A.,Stefely, J.A.,Sukumar, S.,Luna-Sanchez, M.,Jochem, A.,Lew, S.,Seetharaman, J.,Xiao, R.,Wang, H.,Westphall, M.S.,Wrobel, R.L.,Everett, J.K.,Mitchell, J.C.,Lopez, L.C.,Coon, J.J.,Tong, L.,Pagliarini, D.J. Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis. Proc.Natl.Acad.Sci.USA, 111:E4697-E4705, 2014 Cited by PubMed: 25339443 DOI: 10.1073/pnas.1413128111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.393 Å)

Structure validation