4RHP

Crystal structure of human COQ9 in complex with a phospholipid, Northeast Structural Genomics Consortium Target HR5043

4RHP の概要

• エントリーDOI: 10.2210/pdb4rhp/pdb
• 分子名称: Ubiquinone biosynthesis protein COQ9, mitochondrial, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE (3 entities in total)
• 機能のキーワード: structural genomics, psi-biology, northeast structural genomics consortium, nesg, all alpha-helical protein, ubiquinone biosynthesis, mitochondrial, mitochondrial protein partnership, mpp, biosynthetic protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 54875.46

構造登録者

Forouhar, F.,Lew, S.,Seetharaman, J.,Wang, H.,Lee, D.,Kogan, S.,Maglaqui, M.,Xiao, R.,Everett, J.K.,Montelione, G.T.,Hunt, J.F.,Tong, L.,Northeast Structural Genomics Consortium (NESG),Mitochondrial Protein Partnership (MPP) (登録日: 2014-10-02, 公開日: 2014-10-22, 最終更新日: 2019-08-14)

• 主引用文献: Lohman, D.C.,Forouhar, F.,Beebe, E.T.,Stefely, M.S.,Minogue, C.E.,Ulbrich, A.,Stefely, J.A.,Sukumar, S.,Luna-Sanchez, M.,Jochem, A.,Lew, S.,Seetharaman, J.,Xiao, R.,Wang, H.,Westphall, M.S.,Wrobel, R.L.,Everett, J.K.,Mitchell, J.C.,Lopez, L.C.,Coon, J.J.,Tong, L.,Pagliarini, D.J.; Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis.; Proc.Natl.Acad.Sci.USA, 111:E4697-E4705, 2014; PubMed: 25339443; DOI: 10.1073/pnas.1413128111

実験手法

X-RAY DIFFRACTION (2.393 Å)