4RG3
Epsilon-caprolactone-bound crystal structure of cyclohexanone monooxygenase in the Tight conformation
Summary for 4RG3
Entry DOI | 10.2210/pdb4rg3/pdb |
Related | 3GWD 3GWF 3UCL 4RG4 |
Descriptor | Cyclohexanone monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (6 entities in total) |
Functional Keywords | baeyer-villiger monooxygenase, baeyer-villiger oxidation, biocatalysis, flavoprotein, green chemistry, protein engineering, rossmann fold, oxidoreductase, fad, nadph, cyclohexanone, oxygen, cytosolic (bacterial) |
Biological source | Rhodococcus sp. HI-31 |
Total number of polymer chains | 1 |
Total formula weight | 62614.88 |
Authors | Yachnin, B.J.,Berghuis, A.M. (deposition date: 2014-09-29, release date: 2014-10-15, Last modification date: 2023-09-20) |
Primary citation | Yachnin, B.J.,McEvoy, M.B.,MacCuish, R.J.,Morley, K.L.,Lau, P.C.,Berghuis, A.M. Lactone-bound structures of cyclohexanone monooxygenase provide insight into the stereochemistry of catalysis. Acs Chem.Biol., 9:2843-2851, 2014 Cited by PubMed: 25265531DOI: 10.1021/cb500442e PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.94 Å) |
Structure validation
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