4RG3

Epsilon-caprolactone-bound crystal structure of cyclohexanone monooxygenase in the Tight conformation

4RG3 の概要

• エントリーDOI: 10.2210/pdb4rg3/pdb
• 関連するPDBエントリー: 3GWD 3GWF 3UCL 4RG4
• 分子名称: Cyclohexanone monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (6 entities in total)
• 機能のキーワード: baeyer-villiger monooxygenase, baeyer-villiger oxidation, biocatalysis, flavoprotein, green chemistry, protein engineering, rossmann fold, oxidoreductase, fad, nadph, cyclohexanone, oxygen, cytosolic (bacterial)
• 由来する生物種: Rhodococcus sp. HI-31
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 62614.88

構造登録者

Yachnin, B.J.,Berghuis, A.M. (登録日: 2014-09-29, 公開日: 2014-10-15, 最終更新日: 2023-09-20)

• 主引用文献: Yachnin, B.J.,McEvoy, M.B.,MacCuish, R.J.,Morley, K.L.,Lau, P.C.,Berghuis, A.M.; Lactone-bound structures of cyclohexanone monooxygenase provide insight into the stereochemistry of catalysis.; Acs Chem.Biol., 9:2843-2851, 2014; PubMed: 25265531; DOI: 10.1021/cb500442e

実験手法

X-RAY DIFFRACTION (1.94 Å)