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4R8I

High Resolution Structure of a Mirror-Image RNA Oligonucleotide Aptamer in Complex with the Chemokine CCL2

Summary for 4R8I
Entry DOI10.2210/pdb4r8i/pdb
DescriptorC-C motif chemokine 2, Mirror-Image RNA Oligonucleotide Aptamer NOXE36, SODIUM ION, ... (6 entities in total)
Functional Keywordsaptamer spiegelmer l-oligonucleotide, cytokine-rna complex, cytokine/rna
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted: P13500
Total number of polymer chains2
Total formula weight22046.99
Authors
Oberthuer, D.,Achenbach, J.,Gabdulkhakov, A.,Falke, S.,Buchner, K.,Maasch, C.,Rehders, D.,Klussmann, S.,Betzel, C. (deposition date: 2014-09-02, release date: 2015-04-29, Last modification date: 2015-05-06)
Primary citationOberthur, D.,Achenbach, J.,Gabdulkhakov, A.,Buchner, K.,Maasch, C.,Falke, S.,Rehders, D.,Klussmann, S.,Betzel, C.
Crystal structure of a mirror-image L-RNA aptamer (Spiegelmer) in complex with the natural L-protein target CCL2.
Nat Commun, 6:6923-6923, 2015
Cited by
PubMed: 25901662
DOI: 10.1038/ncomms7923
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.05 Å)
Structure validation

217705

数据于2024-03-27公开中

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