4R21
Zebra fish cytochrome P450 17A2 with Progesterone
Summary for 4R21
Entry DOI | 10.2210/pdb4r21/pdb |
Related | 4R1Z 4R20 |
Descriptor | Cytochrome P450 family 17 polypeptide 2, PROTOPORPHYRIN IX CONTAINING FE, PROGESTERONE, ... (4 entities in total) |
Functional Keywords | cytochrome p450 17a2, progesterone, p450 17a2, 17 (alpha)-hydroxylation, steroid biosynthesis, enzyme kinetics, oxidoreductase |
Biological source | Danio rerio (zebrafish) |
Total number of polymer chains | 2 |
Total formula weight | 110154.21 |
Authors | Pallan, P.S.,Egli, M. (deposition date: 2014-08-08, release date: 2014-12-31, Last modification date: 2024-02-28) |
Primary citation | Pallan, P.S.,Nagy, L.D.,Lei, L.,Gonzalez, E.,Kramlinger, V.M.,Azumaya, C.M.,Wawrzak, Z.,Waterman, M.R.,Guengerich, F.P.,Egli, M. Structural and Kinetic Basis of Steroid 17 alpha, 20-Lyase Activity in Teleost Fish Cytochrome P450 17A1 and Its Absence in Cytochrome P450 17A2. J.Biol.Chem., 290:3248-3268, 2015 Cited by PubMed: 25533464DOI: 10.1074/jbc.M114.627265 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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